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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $38 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. |
In vitro | vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide[1]. |
In vivo | Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation[1]. |
Cell Research | For in vitro cytotoxicity experiments, 1×105 TC-1 cells per well are added to 24-well plates. Eighteen hours later, tumor cells are treated with Vitamin E (0, 25, 50 μM). After 18 hours, apoptotic (Annexin V+ and 7AAD−) and necrotic (Annexin V+ and 7AAD+) cells are measured using PE Annexin V Apoptosis Detection Kit I. (Only for Reference) |
Alias | Vitamin E, D-α-Tocopherol, Dexrabeprazole Sodium, Alpha-Tocopherol, 5,7,8-Trimethyltocol, (+)-alpha-Tocopherol |
Molecular Weight | 430.71 |
Formula | C29H50O2 |
Cas No. | 59-02-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 12 mg/mL (27.86 mM) Saline: 25 mg/mL (58.04 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Saline
Saline
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